Evidence that marine-derived, multi-mineral, Aquamin inhibits the NF-κB signaling pathway in vitro

O’Gorman, D. M., O’Carroll, C., and Carmody, R. J. (2012) that marine-derived, multi-mineral, the NF-κB in . Phytotherapy Research, 26(4), pp. 630-2. (doi:10.1002/ptr.3601) (PMID:22034197)

Full text not currently available from Enlighten.

Abstract

It is well established that nuclear factor kappa B (NF-κB) is a central regulator of the immune response and that dysregulation of NF-κB contributes to the pathogenesis of many autoimmune and inflammatory diseases. The food supplement Aquamin is a natural multi-mineral derived from the red algae Lithothamnion corallioides, rich in calcium, magnesium and 72 other trace minerals. This study describes an anti-inflammatory role for Aquamin in inhibiting NF-κB activation through reducing the phosphorylation and degradation of its upstream inhibitor IκBα. Aquamin inhibition of NF-κB activation results in significantly reduced cyclo-oxygenase-2 gene expression following treatment of macrophage cells with lipopolysaccharide. These data suggest that nutritional supplements such as Aquamin may play an important role in regulating the inflammatory response by modulating the nuclear factor kappa B signalling pathway.

http://news360.com/article/331583054

You can follow any responses to this entry through the RSS 2.0 feed. Responses are currently closed, but you can trackback from your own site.

This entry passed through the Full-Text RSS service – if this is your content and you’re reading it on someone else’s site, please read the FAQ at fivefilters.org/content-only/faq.php#.

Herbs and Helpers

Check Also

How frying is ‘HEALTHIER than boiling

#Frying vegetables in extra virgin olive oil increases antioxidants in them Transfers phenols from the ...

Leave a Reply

Your email address will not be published. Required fields are marked *